Make a difference by joining TRC-DS
People with Down syndrome can help find treatments, and one day a cure, for Alzheimer’s disease.
Researchers want to deliver the most promising Alzheimer’s treatments to people with Down syndrome, but they cannot do it alone.
Because people with Down syndrome have the same brain changes as those with Alzheimer’s disease, they are at very high risk for Alzheimer’s disease dementia and are an important population to consider as we develop therapies for Alzheimer’s research.
Who is eligible?
TRC-DS seeks at least 120 people with Down syndrome as volunteers.
Who is Eligible?
Healthy adults between the ages of 35 and 55 with Down syndrome
People interested in supporting clinical research
People who will visit their nearest research center once every 16 months for physical exams like blood pressure checks and blood draws, memory skills tests, and brain scans to measure changes in their brain health and function
Why Down Syndrome?
Interested volunteers should contact their nearest TRC-DS research location
How it works
People with Down syndrome can make a difference in Alzheimer’s research.
The in-person evaluation consists of a physical exam, medical tests (such as a blood draw and brain imaging scans), and memory skills assessments to measure initial brain health and function.
Once evaluated and deemed eligible, volunteers enroll in TRC-DS where they continue in-person visits once every 16 months until deemed eligible for an enrolling Alzheimer’s disease clinical trial.
TRC-DS is funded by the National Institutes of Health’s INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) initiative, in partnership with ACTC-DS and ABC-DS.
The project is led by:
Michael Rafii MD, PhD
Principal Investigator of the NIH-funded Alzheimer’s Clinical Trial Consortium - Down Syndrome (ACTC-DS)
Associate Professor of Clinical Neurology at the University of Southern California’s Keck School of Medicine.